Log P determination - Syrris

Log P determination

The partition co-efficient of an extraction system is particulally important when looking to scale-up a process. The Syrris FLLEX system can rapidly determine log P for a range of different solvent types.

Click here to see the AFRICA flow system.

Click here to see the FRX flow system.

The FLLEX system can be used to test different solvent pairs to determine which is the most efficient for a particular extraction by determining log P.

By changing the flow rate of the solvents into the system, different equilibration times can be tested to find the optimal separation.

Log P studies can be conducted with a system as simple as the FRX schematic below shows.

More sophisticated systems can be used to perform multiple experiments (varying concentrations, temperatures and solvents) to fully explore a range of reaction variables. The AFRICA system is an example of this.