Synthesis in Jacketed Reactors
Why Choose Atlas?
Atlas is the most flexible and easy to use jacketed reactor system available, enabling reactions from -90°C to +250°C. The design saves space and money by allowing 50ml, 100ml, 250ml, 500ml,1L, 2L, 3L and 5L jacketed vessels to be used with same clamp, lid and circulator.
Systems can be set-up easily as no tools are required. Vessels and stirrers can be changed quickly due to the jacket oil drain system, quick vessel clamp, clip on/off auto-aligning stirrer motor and easy adjust stirrer seal and guide. Choose from a wide range of vessel profiles, jacket options, stirrers, sensors and accessories.
The Atlas Base intelligently controls circulators (e.g. Julabo, Huber, etc.) based on in-reaction temperature probes. Sensors such as temperature, pH, turbidity etc. can be plugged into the base. Data is displayed on the base, automatically logged and can be downloaded as one csv file to a USB stick.
Systems can either be manually controlled, automatically controlled by the Atlas Base or fully automated using the Atlas PC Software. Atlas’ modularity allows control of single or parallel jacketed automated reactors.
Atlas can perform automated experiments with or without a PC. Using the front panel controls, set points, ramps or profiles can be set for reaction temperature, stirrer speed and reagent additions. The Atlas PC Software uses a "drag and drop" interface to allow the easy set-up and control of demanding experiments.
Atlas PC Software offers advanced functionality to all Atlas systems. Atlas and other manufacturer’s apparatus can be controlled in sophisticated recipes with real time graphs, alarms and shutdowns. The flexible software allows experiments to be performed in three simple steps: 1. Define apparatus, 2. Create recipe, 3. Run experiment.
Without a PC, Atlas can automatically control experiments with up to 99 steps. The Atlas Base controls reaction temperature, overhead stirrer speed and reagent addition from a pump.
Reagent Addition and Sampling
The Atlas Syringe Pumps (regular up to 20ml/min or XL up to 200ml/min) are versatile dosing and sampling systems. They allow 2 independent refilling flows, one continuous flow, reaction sampling, intelligent control of pH and temperature dependent dosing.
During reagent additions, Atlas Syringe Pumps (shown above) can monitor reaction temperature and pause in the case of an exotherm. By connecting a pH meter, they can monitor and automatically control the pH of a reaction by adding an acid and/or base.
Using the Atlas Autosampler and probe, samples can automatically be aspirated into HPLC vials at defined intervals. Dose with one syringe while sampling with the other.
The Atlas Syringe Pumps can be controlled in standalone mode using the front panel to perform automated processes. Alternatively, they can be connected to an Atlas Base or the Atlas PC Software for sophisticated control.
The wetted parts are made from glass, PTFE and PCTFE allowing the widest range of reagents to be used.
The Atlas Calorimeter accurately measures the power and enthalpy of chemical reactions. This provides reaction kinetics and safety data that is invaluable in process optimization, scale-up and hazard evaluation studies. The Atlas Calorimeter is extremely accurate, easy to use and automatically compensates for changes in UA and the heat of addition.
The Atlas Calorimeter has been designed so heat flow calorimetry (HFC) and power compensation calorimetry (PCC) are performed with the same equipment, allowing a choice of methods for the reaction.
In-reactor temperature probes connected to the circulator enable accurate process temperatures.
Atlas has a range of systems for both crystallization monitoring and control. These offer reproducible control of nucleation, particle size, polymorph selectivity and narrow particle size distribution.
Using Prosonix ultrasound technology, the Sonolab allows repeatable control of nucleation. This allows narrow particle size distribution and control of particle size, shape, crystallinity and polymorphism.
The Atlas Sonolab can be used for ultrasonic wet milling. This offers a scalable technique to access smaller particles with a narrower size distribution.
Atlas allows integration of particle analysis instruments e.g. Particle Visualization and FBRM (Focussed Beam Reflectance Measurement) devices to monitor particle size in real time.
The Atlas Turbidity Probe can be used to monitor crystallization processes with or without a PC. The Atlas PC Software allows it to be used as a control parameter.
For pressure reactions such as hydrogenations, polymerizations, etc. or vacuum applications, Atlas offers two types of pressure vessel: 3 bar jacketed reactors and 200 bar electrically heated reactors. For gas control, options include the Gas Selection Module, Pressure Control Module and mass flow meters or controllers.
Easy to use reactor for applications where pressures up to 3 bar and temperatures from -80°C to +200°C are required. Available in vessels sizes from 100ml to 3L, with or without vacuum jacket.
The Gas Selection Module allows 3 gases to be permanently connected to the module yet only one gas connected to the reactor at any one time.
This module automatically controls the dosing of gas into the reactor. Commands include; control pressure, purge and vent.
Ideal for applications where pressures up to 200 bar and reaction temperatures up to 320°C are required. Available in stainless steel 316, hastelloy and titanium and in vessel sizes from 100ml to 450ml.