Atlas SonoLab - Syrris - Crystallization Control and Sonochemistry

The Atlas SonoLab is a high performance, automated ultrasound system for sonocrystallization, sonomilling and sonochemistry. The proprietary ultrasound technology with novel transducer based design, allows reproducible control of crystallizations, enabling selectivity of parameters such as particle size, shape, crystallinity and polymorphism.

• Selective: Significantly improved polymorph, particle size and particle shape selectivity.
• Narrow particle size distribution: Advanced control of nucleation and growth rate results in very narrow particle size distribution.
• High purity: Sophisticated control results in reduced impurities and trapped solvents.
• Reproducible: Automated control of process parameters and nucleation improves batch to batch consistency.
• Scalable: Optimized crystallizations on a laboratory scale can be scaled to pilot plant processes and manufacturing using the ProsonitronTM range of products from Prosonix Ltd.
• Product quality improvement: Improved formulation consistency, stability and performance of final drug products.
• No seeding required: Removing the need for seed crystals avoids issues with consistency and access to the reactor.
• Easy to use: No tools required, intuitive “drag and drop” Atlas software and real time data graphed during process.
• Excellent temperature control: Sophisticated PID temperature control and accurate sensor feedback results in accurate process performance.
• Advanced automation: With the Atlas PC software, the system can introduce ultrasound at accurate temperature points within and around the metastable zone.
• Integrated turbidity or FBRM analysis: The Atlas Software allows integration of the Syrris Turbidity Probe or FBRM characterization.