Testimonials - Syrris - Batch and Flow Chemistry Systems

“Great for scaling up, in a safe and comfortable way!”

Freek Vrielynck (Senior Scientist, EcoSynth, Belgium)

“We work with zirconium compounds, which are ink additives for the packing industry, and also perform drug discovery studies. We use a range of vessels – from 100ml up to 2L – with our Atlas Calorimeter which, like our 100L pilot system, has been tailored to scale-up experiments and studies in support of this work. The results obtained are fundamental to performing the technological transfer of the procedures to the production plant.”

“...the systems are well designed and the software is very functional, efficient and easy to use, with a robust communication protocol...”

“We evaluated equivalent systems from a number of manufacturers prior to purchasing the Atlas Calorimeter and 100L systems. Syrris arranged a demonstration of one of its reactor systems in our laboratory and explained its technological capabilities; this was really important to us, as it allowed us to see and test the product ourselves before we decided which system to buy.”

“The systems are well designed and the software is very functional, efficient and easy to use, with a robust communication protocol. User-friendly operation allows us to train staff rapidly. The performance and reliability of both systems is really good, and we are now considering purchasing an Asia flow system to complement our existing Syrris equipment.”

Valter Russo (Director of R&D, Zirkon Industria e Comercio Ltda, Brazil)

“We purchased an Atlas Calorimeter last year, and use it every day to validate new approaches, test new reactions and check whether a particular catalyst or component is active. It enables us to try small-scale reactions before moving to a large-scale pilot plant”

“Before we had the Atlas system we used conventional labware and oil baths, which required close monitoring. With the Atlas, we can leave experiments running all night and get a good result the next day, freeing up time to do other tasks. The system is easy to use and reliable – we know that when we move from the Atlas system to the large-scale plant we will get very similar results – and the software is just beautiful.”

“...and the software is just beautiful...”

“Syrris also worked with us to develop customized stirrers and baffles specifically for our work, and we were able to get what we needed in a reasonable time and for a reasonable price. Our Atlas system has been so successful that we plan to purchase another one in the near future.”

Onofre Casanova (Chemical Process Engineer, IFF, Benicarlo, Spain)

“Since investing in the Atlas from Syrris, we have been delighted at the rapid uptake by our chemists and the high demand that they have placed for available systems.”

“We are also very impressed with the speed and quality of the service and support.”

Dr. Phil Peach (Process CRD, Pfizer, UK)

“We synthesize catalysts for the production of polyolefins such as polyethylene and polypropylene, and test the polymerization in slurry and gas phase processes. To help with this work, we have invested in Atlas modular products, which are very adaptable and can form a wide range of chemical reactors.”

“We run two Atlas 3 bar reactor systems in parallel, and can quickly and easily configure the reactors for advanced applications such as calorimetry and crystallization control. The whole system is controlled by the intuitive Atlas Parallel Software, which automatically detects which apparatus is connected.”

“...our Atlas reactors are in use every working day, and the system is very reliable. It offers great reproducibility...”

“Syrris offers a variety of different vessels – including triple-jacketed vessels and round bottom flasks – which makes it easy to scale up reactions. Our Atlas reactors are in use every working day, and the system is very reliable. It offers great reproducibility, and its glass jacketed reactors allow us to follow both the polymerization reaction and the synthesis process.”

“We also receive good support from both Sithiphorn, our local distributor, and Syrris, which we really appreciate; they always care about the little things that are important to the customer, and work with them to meet the specific demands of their applications.”

Supabhorn Korboonsungserm (Researcher in Process Technology, PTT, Thailand)

“We purchased two Atlas systems, and are delighted with their performance, ease of use and flexibility.”

David Easson (VP Manufacturing and Process Dev. at Epic Therapeutics, Baxter Healthcare, USA)

“We have found Atlas to be extremely versatile and the ability to re-configure the system as projects demand change is very powerful. Applications such as turbidity, pH control, distillation and calorimetry have been made easy with Atlas.”

“...we have also received excellent post-sales support and technical help from Syrris...”

“We have also received excellent post-sales support and technical help from Syrris. We have been very impressed with the Atlas software and find the ability to seamlessly integrate and control 3rd party equipment to be particularly important when designing experiments.”

Ben Brockbank (Process Development - Syngenta Ltd, UK)

“We at Torrent bought a Syrris Parallel Atlas jacketed reactor system and found that the Atlas Reactor platform is extremely flexible, powerful and user friendly system. This system has now become core to our Chemical Research. We are continuing to upgrade the Atlas systems with more functionality to perform Reaction Calorimetry and Turbidity probes for crystallization studies.”

“...the Atlas Reactor platform is extremely flexible, powerful and user-friendly...”

“One key to our success with the Atlas system apart from the strength of the product itself is the highly responsive nature of Syrris as a company. Syrris has now developed new functionality together with Torrent. In addition with Syrris now having an Indian subsidiary, we also have a pool of highly knowledgeable people in India who can resolve issues with us very quickly.”

“Torrent is very pleased with Syrris as a company and our experience of the Atlas product line is very positive and we sincerely believe that this would be a continuous and consistent feature.”

Dr. Sunil S. Nadkarni (VP, Product Development Torrent, India)

“Overall, we have been exceedingly pleased with the Syrris Asia pumps. We have found the system suitable for pumping reagents incompatible with other pumping systems, specifically reagents incompatible with stainless steel components. Furthermore, the range of flow rates achievable and the reasonably high pressure tolerances of the Asia system make this pump highly versatile, suiting the majority of our chemistry needs.”

“...we have found the system suitable for pumping reagents incompatible with other pumping systems, specifically reagents incompatible with stainless steel components...”

“In addition to the outstanding quality of the Syrris equipment, the sales and support staff have been exceptionally attentive; addressing any concern or problem in a timely and professional manner. The quality of service we have received from Syrris has been second to none.”

Dr. Andy Kleinke (Postdoctoral Researcher)

“We trialed our nanoparticle experiments on the Asia flow chemistry system during a visit to Syrris’ UK facilities, and immediately placed an order for our own system.”

“We are looking forward to performing our synthesis on the Asia, which will help us to optimize the speed and results of our synthesis workflow.”

Paulina Lloret (Researcher, INTI, Argentina)

“In discovery chemistry research, we need to perform a lot of very interesting and complex chemical syntheses and, until now, have relied on classical batch chemistry methods.”

“We purchased an Asia flow chemistry reactor in June, and are now reaping the benefits of using flow chemistry techniques. The system has extended the range of chemistries available to us, allowing us to work at much higher pressures and temperatures – sometimes above a solvent’s boiling point – to create completely new heterocyclic scaffolds.”

“We can combine the Asia modules in a variety of different ways to meet changing needs, and will also be able to add additional modules at a later date if required. This was an important consideration, and one of the main reasons for choosing Asia.”

“...in my opinion, Syrris is as innovative in the synthetic chemistry arena as Google or Apple in the informatics field...”

“Syrris has been very supportive, giving us some valuable ideas and flow chemistry tips during our training, and we can now do chemistry which was absolutely impossible before. In my opinion, Syrris is as innovative in the synthetic chemistry arena as Google or Apple in the informatics field.”

Dr György Túrós (Research Scientist, Gedeon Richter, Hungary)

“Our department is dedicated to teaching and research into organic chemistry, and wanted a continuous flow system to perform biocatalytic reactions. We needed a flow chemistry system that would enable us to load catalysts onto a packed bed easily, and the Asia system has proved ideal.”

“...the system is running seven days a week, and is so popular that people are queuing up to use it...”

“We purchased the Asia system a year ago, and found it easy to implement in our laboratory. It is a very user-friendly system, and the wide range of flow rates offered by the Asia Pump is a big advantage. We also have the capability to load the solid phase column reactors with our own catalysts, which is another great benefit.”

“The system is running seven days a week, and is so popular that people are queuing up to use it. The Asia system helped us to become the first group at the University – and in Brazil – to develop biocatalyzed continuous flow reactions, and we now plan to buy another similar system to help meet the needs of our laboratory.”

Dr Rodrigo Souza (Associate Professor in Organic Chemistry, UFRJ, Brazil)

“We use the Asia flow chemistry system for work targeted at the synthesis of a natural product, and it is essential that we are able to undertake multi-step processes. The modular design of the Asia system is very helpful, allowing us to rearrange it into different configurations to suit whatever multi-step synthesis sequence we need to perform.”

“...the flexibility to change syringes enables anything from very small scale to large scale synthesis to be achieved...”

“The major advantage of the Asia system is the accuracy of its pumps at low flow rates – as low as 1 µl/min – which allows us to perform flow reactions on milligram quantities of material, and the flexibility to change syringes enables anything from very small scale to large scale synthesis to be achieved. It is very easy to exclude water from the system, allowing organometallic reactions to be set up more rapidly.”

“The pressurised inlet for the pumps is also extremely useful for these reactions – pumping organometallic compounds can be problematic in flow chemistry giving us the confidence to try things that we would not previously have attempted and helping to reduce failure rates.”

Catherine Carter (Ley Group, University of Cambridge, UK)

“We have employed the Syrris FLLEX module as a "copper extraction device". The flexibility to connect the FLLEX module to our existing microflow apparati was key for success in this project.”

“This was the first published application from our group concerning the FLLEX system and more is still in the pipeline.”

Click here to read the paper, as published in ChemSusChem.

Dr. Timothy Noël (Eindhoven University of Technology, Netherlands)

“Ideal for evaluation of kinetics of temperature sensitive fast reactions. The whole system is controlled via a user friendly Reaction Manager Software and Windows driven PC.”

Mark R. Bailey (Eli Lilly & Co, IN, USA)

“The Africa system has proved to be a valuable addition to our machinery for instrumented assisted synthesis. Especially, the easy to use software which allows very simple configuration of different reaction set ups makes the system extremely user friendly. Also for reaction optimization the software and the robotic system with two autosamplers is extremely useful and allows efficient library synthesis.”

“...the robotic system with two autosamplers is extremely useful and allows efficient library synthesis...”

“Additionally, the support from Syrris which we have experienced is of the highest quality. This is invaluable, especially when you start to use a new system and you need quickly an advice how to handle a certain problem. Overall, we are very happy with the system and are exploring more and more of the possibilities the system offers and still have not exhausted all the features.”

Michael Schnürch (Institute of Applied Synthetic Chemistry, Vienna University of Technology, Austria)

“A multiday, multistep preparative procedure has been shortened to a matter of minutes”

Dr. Daniel Grant (Burnham Institute, CA, USA)

“A safe and readily accessible substitute for ethyl azide has been identified and its usefulness demonstrated in a [3 + 2]-cycloaddition design space evaluation using the Syrris Africa continuous flow reactor setup.”

Dr. Rob Tinder (Wyeth Research Chemical Development, NY, USA)

“While using the Syrris Africa system, it quickly becomes obvious that this advancing technology is prime for both pharma and academic drug discovery efforts. It’s sheer flexibility allows for countless reaction configurations through use of microchip, fixed-bed, and tubular reactors with multiple, high profile modules on hand for ‘as needed’ integration.”

“...great for discovery and reaction optimization...”

“The automated reagent injection module is great for discovery and reaction optimization as multiple reagents, catalysts, or substrates can effectively be screened in a single, automated reaction sequence. This results in rapid optimization and the possibility of discovering new substrate/catalyst reactivity patterns within any given system.”

“On top of these valued attributes, our laboratory gives the Syrris’ post sales support team an A+ for their timely communication and high-level troubleshooting efforts.”

Toby R. Long, Ph.D., (Sanford-Burnham Institute, FL, USA)

“Syrris is a pioneer in the development of technology that is empowering chemists in both industry and academia.”

Nicholas Cosford, Ph.D., (Sanford-Burnham Institute, CA, USA)