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Flow Products Africa Flow Chemistry 4 Channel Synthesis
Flow Products Africa Flow Chemistry 4 Channel Synthesis
Africa 4 Channel Synthesis - Syrris - Automated Flow Chemistry
4 Channel Synthesis (S) System
The 4 Channel Synthesis System enables pressurised flow reactions with 4 independently controlled substrate/reagent inputs and two reaction locations, independently temperature controlled.
The 4 Channel Synthesis System (S) is ideal for use in the following applications:
- Medicinal chemistry
- Flow chemistry investigations
- Intermediate production
- Synthetic conditions not possible in regular batch chemistry
- Process chemistry
- Reaction optimisation (manual collections)
- Early scale-up
- Degradation testing
- Stability studies
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Specification
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4 Syringe Pumps: |
Flow rate 2.5µl to 2.5ml/min with pressure sensors and automatic over-pressure shutdown |
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4 Pressurized Input Bottles: |
Regulated 1 bar Nitrogen or Argon is supplied to up to 4 bottles, eliminating cavitation and bubble formation and allowing the use of air sensitive reagents (requires laboratory gas supply). |
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4 Manual Injection Loops and Valves: |
1ml, 5ml or 10ml loops |
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Chemical Resistance: |
All wetted parts are glass, PTFE or other similar fluoropolymer. |
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2 Temperature Controlled Microreactor Positions: |
The Africa Heater/Cooler has two reaction positions, each of which can be factory set to either:
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Automation: |
The Africa software allows an almost unlimited number of reactor configurations and automates the entire process. Only “chemist friendly” data such as volumes, times and temperatures need to be added – no need to deal with flow rates if you don’t want to. The timings of all events such as pumps starting, injections, collections etc. are all automatically calculated. |
Parts
The 4 Channel Synthesis (S) System contains the following modules, click on the part number for more information: