Africa Full System - Syrris - Fully Automated Flow Synthesis
Full AFRICA System


The full Africa Synthesis, Analysis, Liquid Handling and FLLEX (SAHF) System enables entirely automated flow synthesis, analysis, aqueous work up, reagent injection and product collection.
The full Africa Synthesis, Analysis, Liquid Handling and FLLEX (SAHF) System is ideal for use in the following applications:
- Medicinal Chemistry
- Log D determination (fully automated)
- Library production (fully automated) - Process Chemistry
- Log P determination (fully automated)
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Specification
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2 Syringe Pumps: |
Flow rate 2.5ul to 2.5ml/min with pressure sensors and automatic over-pressure shutdown |
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4 Pressurized Input Bottles: |
Regulated 1 bar Nitrogen or Argon is supplied to up to 4 bottles, eliminating cavitation and bubble formation and allowing the use of air sensitive reagents (requires laboratory gas supply). |
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Automatic Reagent Injection: |
The RIM allows reagents stored on the robot deck to be automatically aspirated and loaded into one of 4 injection loops. The robot has a coaxial needle allowing the use of air sensitive reagents in vials. All timings are automatically managed, even for complex, multi-reactor systems. Samples are pre-pressurized before injection into the flowing stream. |
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Chemical Resistance: |
All wetted parts are glass, PTFE or other similar fluoropolymer. |
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2 Temperature Controlled Microreactor Positions: |
The Africa Heater/Cooler has two reaction positions, each of which can be factory set to either:
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Flow Liquid-Liquid Extraction: |
Flow extraction and separation of an extremely wide range of immiscible solvent pairs e.g. DCM:Aq, Ethyl Acetate:Aq, THF:Aq, Ether:Aq etc. (where Aq is aqueous). |
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Reaction Sampling: |
The Sampler and dilutor takes a 5ul sample from the flowing stream, dilutes it by up to 250 fold and injects it onto an analytical system e.g. HPLC, LCMS, UPLC etc. |
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HPLC Analysis: |
The Africa HPLC allows integrated synthesis conditions an HPLC traces. |
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Automated Product Collection: |
Each different reaction is automatically collected in a different |
Parts
The full Africa Synthesis, Analysis, Liquid Handling and FLLEX (SAHF) contains the following modules, click on the part number for more information:


