Africa Synthesis and Liquid Handling - Syrris - Flow Synthesis

Flow rate 2.5µl to 2.5ml/min with pressure sensors and automatic over-pressure shutdown

Regulated 1 bar Nitrogen or Argon is supplied to up to 4 bottles, eliminating cavitation and bubble formation and allowing the use of air sensitive reagents (requires laboratory gas supply).

The RIM allows reagents stored on the robot deck to be automatically aspirated and loaded into one of 4 injection loops. The robot has a coaxial needle allowing the use of air sensitive reagents in vials. All timings are automatically managed, even for complex, multi-reactor systems. Samples are pre-pressurized before injection into the flowing stream.

All wetted parts are glass, PTFE or other similar fluoropolymer.

The Africa Heater/Cooler has two reaction positions, each of which can be factory set to either:

• 0°C – 150°C
• 40°C – 250°C

Each different reaction is automatically collected in a different vial. The vial (or vessel) size is set by the user. Reactions larger than the vial size are automatically collected across multiple vials or preparative quantities can be collected in large one vessel.

The Africa software allows an almost unlimited number of reactor configurations and automates the entire process. Only “chemist friendly” data such as volumes, times and temperatures need to be added – no need to deal with flow rates if you don’t want to. The timings of all events such as pumps starting, injections, collections etc. are all automatically calculated and performed automatically.