Africa Synthesis and FLLEX System - Syrris
Synthesis and FLLEX (SF) System


The Synthesis and FLLEX (SF) System enables pressurised flow reactions with 4 independently controlled substrate/reagent inputs, two independently temperature controlled reaction locations and aqueous work-up.
The Synthesis and FLLEX (SF) System is ideal for use in the following applications:
- Medicinal chemistry
- Log D determination (controlled chemistry) - Process chemistry
- Log P determination (controlled chemistry)
Click here to download product information or contact us.
Specification
|
4 Syringe Pumps: |
Flow rate 2.5µl to 2.5ml/min with pressure sensors and automatic over-pressure shutdown |
|
4 Pressurized Input Bottles: |
Regulated 1 bar Nitrogen or Argon is supplied to up to 4 bottles, eliminating cavitation and bubble formation and allowing the use of air sensitive reagents (requires laboratory gas supply). |
|
4 Manual Injection Loops and Valves: |
1ml, 5ml or 10ml loops |
|
Chemical Resistance – |
All wetted parts are glass, PTFE or other similar fluoropolymer. |
|
2 Temperature Controlled Microreactor Positions: |
The Africa Heater/Cooler has two reaction positions, each of which can be factory set to either:
|
|
Flow Liquid-Liquid Extraction: |
Flow extraction and separation of an extremely wide range of immiscible solvent pairs e.g. DCM:Aq, Ethyl Acetate:Aq, THF:Aq, Ether:Aq etc. (where Aq is aqueous). |
|
Automation: |
The Africa software allows an almost unlimited number of reactor configurations and automates the entire process. Only “chemist friendly” data such as volumes, times and temperatures need to be added – no need to deal with flow rates if you don’t want to. The timings of all events such as pumps starting, injections, collections etc. are all automatically calculated and performed automatically. |
Parts
The Synthesis and FLLEX System (SF) contains the following modules, click on the part number for more information:


