Africa Synthesis, FLLEX and Product Collection - Syrris
Synthesis, FLLEX and Product Collection


The Synthesis, FLLEX and Collection (SFC) System enables pressurised flow reactions with 4 independently controlled substrate/reagent inputs, two independently temperature controlled reaction locations, aqueous work-up and automated product collection.
The Synthesis, FLLEX and Collection (SFC) System is ideal for use in the following applications:
- Medicinal chemistry
- Log D determination (semi automated) - Process chemistry
- Log P determination (semi automated)
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Specification
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4 Syringe Pumps: |
Flow rate 2.5µl to 2.5ml/min with pressure sensors and automatic over-pressure shutdown |
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4 Pressurized Input Bottles: |
Regulated 1 bar Nitrogen or Argon is supplied to up to 4 bottles, eliminating cavitation and bubble formation and allowing the use of air sensitive reagents (requires laboratory gas supply). |
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4 Manual Injection Loops and Valves: |
1ml, 5ml or 10ml loops |
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Chemical Resistance: |
All wetted parts are glass, PTFE or other similar fluoropolymer. |
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2 Temperature Controlled Microreactor Positions: |
The Africa Heater/Cooler has two reaction positions, each of which can be factory set to either:
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Flow Liquid-Liquid Extraction: |
Flow extraction and separation of an extremely wide range of immiscible solvent pairs e.g. DCM:Aq, Ethyl Acetate:Aq, THF:Aq, Ether:Aq etc. (where Aq is aqueous). |
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Automated Product Collection: |
Each different reaction is automatically collected in a different vial. The vial (or vessel) size is set by the user. Reactions larger than the vial size are automatically collected across multiple vials or preparative quantities can be collected in large one vessel. |
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Automation: |
The Africa software allows an almost unlimited number of reactor configurations and automates the entire process. Only “chemist friendly” data such as volumes, times and temperatures need to be added – no need to deal with flow rates if you don’t want to. The timings of all events such as pumps starting, injections, collections etc. are all automatically calculated and performed automatically. |
Parts
The Synthesis, FLLEX and Collection (SFC) System contains the following modules, click on the part number for more information:


