The Syrris Africa LogP/LogD (log) System enables entirely automated partitioning and separation of samples for logP and logD studies with optional analysis. At the heart of the system lies the FLLEX (Flow Liquid Liquid EXtraction) Module which flows two immiscible liquids together with rapid partitioning and separation at a microfluidic scale.
The correlation between the Africa LogP/LogD System and the traditional shake flask method is excellent. Click here to see the J. Med. Chem paper written by Pfizer Inc.
The LogP/logD system can be used to either gather samples for logP/D measurement offline or can include the Africa HPLC system for direct analysis of concentrations in samples separated by the FLLEX.
An Africa LogP/LogD System contains the following modules. Click on the individual modules to find out more.