Reagent Injection - Africa Flow Chemistry Modules - Syrris

The Reagent Injection modules together enable fully automated aspiration of up to 100s of solutions from a robot deck and subsequent timed injection into the flow reactor.

The modules consist of a Gilson autosampler, RIM:Feed (Reagent Injection Module: Feed) and RIM:Loops (Reagent Injection Module:Loops).

Together they enable hundreds of compounds to be injected into the flow reactor under pressure, separated by a solvent analogous to bullets down the barrel of a machine gun. The Reagent Injection Modules can inject multiple reactions into the flowing stream in a fast serial fashion so that several reactions are in the system at a time.

The injection timing of up to four components per reaction is fully controlled by the software to ensure samples meet in the reactor(s) at the correct time.

Lists of reagents/substrates can be imported into the software from .csv files and their volume tracked during use enabling full resource management.

These modules are suited to the following applications: synthetic libraries, reagent screening, reaction optimisation, kinetic studies, degradation studies, logD screening, etc.

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