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Syrris in Publications - Syrris

Fluorination reactions in microreactors

Chem. Commun., 2008, 3022-3024

Tomas Gustafsson, Ryan Gilmour and Peter H. Seeberger*
Swiss Federal Institute of Technology, Zurich, Laboratorium für Organische Chemie, Switzerland


This paper describes a fast, safe and continuous fluorination protocol using DAST for primary alcohols, carboxylic acids and aldehydes conducted in a Syrris Tube Reactor on a Syrris FRX system.

Fluorination Reactions in Microreactors

Abstract: The DAST-mediated conversion of a range of alcohols to the corresponding fluorides in a microstructured device is described. This safe, practical fluorination method will facilitate reactions currently challenging on large scale.

To download the paper click here


FRX Flow Chemistry System

This paper was performed on an FRX system. Read about Syrris' current flow chemistry products:

  • Africa Flow Chemistry Overview
  • Asia Flow Chemistry

For more information, contact us.

 

More...

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Thursday, 10 November 2011

Biofuels Continuous Production

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Friday, 09 September 2011

An Automated Process for a Sequential Heterocycle/Multicomponent Reaction: Multistep Continuous Flow Synthesis of 5-(Thiazol-2-yl)-3,4-Dihydropyrimidin-2(1H)-ones

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Friday, 24 June 2011

Flow chemistry moves to Asia

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Tuesday, 15 March 2011

Automated Generation and Reactions of 3-Hydroxymethylindoles in Continuous-Flow Microreactors

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Thursday, 03 February 2011

Continuous Biodiesel Production with Continuous Liquid-Liquid Extraction and Online MS Analysis

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Wednesday, 19 January 2011

Facile, Fast and Safe Process Development of Nitration and Bromination Reactions Using Continuous Flow Reactors

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Thursday, 18 November 2010

One-Step Flow Synthesis of Substituted Pyrrole-3-carboxylic Acid Derivatives via in Situ Hydrolysis of tert-Butyl Esters

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Friday, 15 October 2010

Fully Automated Continuous Flow Synthesis of Highly Functionalized Imidazo[1,2-a] Heterocycles

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Friday, 30 April 2010

Continuous flow processing from microreactors to mesoscale: the Bohlmann–Rahtz cyclodehydration reaction

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Wednesday, 25 November 2009

Synthesis of Gold Nanoparticles in a Flow Microreactor

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Thursday, 02 July 2009

Synthon for Ethyl Azide and Its Evaluation in a [3 + 2]-Cycloaddition Reaction under Continuous-Flow Conditions

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Tuesday, 09 September 2008

Determination of log D via Automated Microfluidic Liquid−Liquid Extraction

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Wednesday, 11 June 2008

Rapid Multistep Synthesis of 1,2,4-Oxadiazoles in a Single Microreactor Sequence - Journal of Organic Chemistry

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Monday, 07 April 2008

Flow Chemistry and Synthesis - KJEMI

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Thursday, 03 January 2008

Evaluation of microfluidics reactor technology on the kinetics of virus inactivation - Biotechnology and Bioengineering

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