Midatech use Atlas reactors to produce gold nanoparticles for pharmaceutical applications

Midatech Biogune, a Spanish biotechnology company, are using Syrris Atlas automated jacketed reactor systems to produce custom-made functionalized gold nanoparticles for medicinal use.

Justin Barry, Midatech’s CEO, explained how the Atlas jacketed reactors are helping their chemists working in the pharmaceutical field:

“Midatech is a clinical-stage biotechnology company focused on translating its proprietary gold nanoparticle drug delivery platform into effective nanomedicines targeting currently unmet medical needs. We begin by producing functionalized gold nanoparticles on a bench scale, then move to larger scale manufacturing processes, where it makes sense to use a reactor system.

Our Atlas Potassium reactors, with pH control and an Atlas Syringe Pump XL, have allowed us to scale­up production, enabling variables such as pH and temperature to be tightly controlled.

The Atlas Potassium was the only logical way to move from manufacturing nanoparticles on a laboratory scale to a mini production environment. It is a reliable and reproducible reactor system that is well assembled, compact and portable, and performs exactly as we were told it would. Atlas Potassium is also very flexible, accommodating volumes ranging from 50 mL to 5 liters, and its operating software works well, enabling a series of validation runs to be performed quickly and easily. The Atlas jacketed reactors were easy to implement in our lab and it took just 6 to 8 months to establish a validated process. We are very happy with them.”

Our Atlas Potassium reactors, with pH control and an Atlas Syringe Pump XL, have allowed us to scale­up production, enabling variables such as pH and temperature to be tightly controlled.

Justin Barry, CEO, Midatech

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Midatech used the Atlas reactor system which has since been upgraded to the Atlas HD automated jacketed reactor system with integrated, intuitive touchscreen control and automation. Discover more here.

To discuss Atlas HD or its uses in pharmaceutical drug development, nanoparticle synthesis, or other areas of chemistry, contact us today to speak to a Syrris chemist.
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