Chemistry in Flow - Flow Chemistry - Syrris

Chemistry in Flow

The list below shows some of the reactions that have been performed on the Asia, Africa and FRX systems. For details on publications that have used Syrris flow chemistry systems, please click here.

Homogeneous catalysis

• Suzuki reaction
• Heck reaction
• Grubbs metathesis

Multicomponent reactions

• Passerini 3CR
• Biginelli 3CR
• Ugi 4CR

Deprotection chemistry

• BOC deprotection
• MOM deprotection and intra epoxide opening
• Ester saponification

Ring formations

• Grubbs metathesis
• Ugi followed by ring closure
• Diels Alder
• 1,3,4 Oxadiazole formation
• Fischer indole synthesis
• 1,3 Thioamidozole formation

Oxidations and reductions

• Borohydride reduction
• Borane reduction of a heterocycle
• Reductive amination
• Dess Martin alcohol oxidation

General syntheses

• Aldol reaction
• Biphasic Schotten-Baumann
• HBTU amide coupling
• Elimination of an alcohol to alkene
• Esterification of an alcohol
• Wittig reaction
• Nucleophilic aromatic substitution
• SN1 reaction
• Mitsunobu reaction