Nanoparticle Synthesis - Syrris

Nanoparticle Synthesis

Syrris flow systems and micromixers are ideally suited to nanoparticle synthesis

Microreactors have shown application in nanoparticle synthesis - their very rapid mixing and excellent temperature control give consistent and narrow particle size distribution. Syrris’ existing customers have synthesised gold nanoparticles and silica nanoparticles.

For information on Syrris flow chemistry products that are ideal for nanoparticle synthesis, click on Asia, Africa or FRX.

To synthesise a consistent sized nanoparticle and/or to produce a consistent covalently derivatised particle it is essential to have:

• Excellent control of conditions:
  • No temperature gradients
  • No concentration gradients
• Efficient and controlled mixing

This ensures a constant rate of reaction throughout the reactor and therefore a consistent nanoparticle – microreactors achieve this every time.

Segmented flow in microreactors can also be used as a method to combat dispersion along channels and to promote mixing (Tice, J.D. et al. Langmuir 2003 19, 9127-8133).

Features of a continuous microreactor system

1. Precise control of temperature – easily set and changed - no temperature gradients
2. Precise control of time - easily set and changed – quick hot reactions for consistent particle size
3. Precise control of feeds/stoichiometry – rapidly investigate stoichiometry by changing feed rates
4. Consistent and rapid mixing – ensures nucleation not precipitation
5. No scale limitations – small scale for optimisation; or “leave tap running” to make kilograms per day (100g/hr readily achievable)
6. Reproducible – same temperature, same mixing, same reaction time, every time
7. Immediate aqueous work up – simple work up available if required

For more information about nanoparticle synthesis, please contact us